The GTF2H2C Polyclonal Antibody (CAB5239) is a valuable tool for researchers studying GTF2H2C, a subunit of the general transcription factor IIH (TFIIH) complex involved in transcription regulation. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By binding to the GTF2H2C protein, this antibody enables the detection and analysis of GTF2H2C in various cell types, making it ideal for studies in molecular biology and gene expression research.GTF2H2C is a crucial component of the TFIIH complex, which plays a key role in transcription initiation and DNA repair processes.
Dysregulation of TFIIH function has been implicated in various diseases, including cancer and neurological disorders. Therefore, understanding the function and regulation of GTF2H2C is essential for uncovering the mechanisms underlying these conditions and developing targeted therapies.Overall, the GTF2H2C Polyclonal Antibody (CAB5239) is a reliable tool for researchers investigating the role of GTF2H2C in gene expression and disease pathogenesis. Its high specificity and sensitivity make it a valuable asset in the study of transcriptional regulation and potential therapeutic targets.
Product Name:
GTF2H2C Rabbit Polyclonal Antibody
SKU:
CAB5239
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human GTF2H2C (NP_001092198.1).
Predicted to enable zinc ion binding activity. Predicted to be involved in nucleotide-excision repair and regulation of transcription by RNA polymerase II. Located in nuclear speck.
Purification Method:
Affinity purification
Gene ID:
728340
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of lysates from LO2 cells, using GTF2H2C Rabbit pAb (CAB5239) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 5s.
