The GTF2H1 Polyclonal Antibody (CAB6814) is a valuable tool for researchers studying GTF2H1, a crucial factor in transcription and DNA repair processes. This antibody, produced in rabbits, exhibits high specificity and sensitivity towards human GTF2H1 protein samples, making it ideal for Western blot applications. By binding specifically to GTF2H1, researchers can accurately analyze and detect the protein in various cell types, facilitating studies in molecular biology and cancer research.GTF2H1, also known as General Transcription Factor IIH Subunit 1, plays a vital role in transcription initiation and nucleotide excision repair mechanisms.
Its involvement in DNA damage recognition and repair processes underscores its importance in maintaining genomic stability and preventing mutations that can lead to diseases like cancer. By investigating the function of GTF2H1, researchers can gain insights into the molecular mechanisms underlying DNA transcription and repair, potentially leading to the development of novel therapeutic strategies targeting these pathways.
Product Name:
GTF2H1 Rabbit Polyclonal Antibody
SKU:
CAB6814
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-425 of human GTF2H1 (NP_001135779.1).
Enables thyroid hormone receptor binding activity. Involved in positive regulation of transcription, DNA-templated and transcription by RNA polymerase II. Located in nucleoplasm. Part of transcription factor TFIIH core complex and transcription factor TFIIH holo complex.
Purification Method:
Affinity purification
Gene ID:
2965
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using GTF2H1 antibody (CAB6814) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
