The GTF2F1 Polyclonal Antibody (CAB19315) is a valuable tool for researchers studying the GTF2F1 protein, a key player in transcriptional regulation and DNA repair processes. This antibody, generated in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to the GTF2F1 protein, this antibody enables precise detection and analysis in a variety of cell types, making it an essential component for studies in molecular biology and cancer research.GTF2F1, also known as General Transcription Factor IIF, is a critical factor in the initiation of transcription by RNA polymerase II.
Its involvement in DNA repair mechanisms further underscores its importance in maintaining genomic stability and preventing mutagenesis. Research on GTF2F1 is essential for understanding gene expression regulation and identifying potential targets for therapeutic interventions in diseases such as cancer and genetic disorders. By utilizing the GTF2F1 Polyclonal Antibody, researchers can further elucidate the role of this protein in cellular processes and advance our knowledge of transcriptional control mechanisms.
Product Name:
GTF2F1 Rabbit Polyclonal Antibody
SKU:
CAB19315
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 390-517 of GTF2F1 (NP_002087.2).
Enables several functions, including RNA polymerase II general transcription initiation factor activity; phosphatase activator activity; and promoter-specific chromatin binding activity. Involved in several processes, including positive regulation of transcription by RNA polymerase II; response to virus; and transcription initiation from RNA polymerase II promoter. Located in cell junction and nucleoplasm. Part of transcription factor TFIID complex.
Purification Method:
Affinity purification
Gene ID:
2962
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using GTF2F1 Rabbit pAb (CAB19315) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.