The GTF2E2 Polyclonal Antibody (CAB8732) is a valuable tool for researchers studying GTF2E2, a key protein involved in the process of transcription initiation. This antibody, generated in rabbits, exhibits high reactivity with human samples and is suitable for use in Western blot applications. By specifically binding to the GTF2E2 protein, this antibody enables the detection and analysis of GTF2E2 in a variety of cell types, making it ideal for investigations in the fields of molecular biology and gene regulation.GTF2E2, also known as general transcription factor IIE subunit 2, plays a crucial role in the initiation of transcription by RNA polymerase II. Its functions are essential for the accurate and efficient production of mRNA, making it a key player in gene expression processes.
Research on GTF2E2 is important for understanding the mechanisms of transcriptional regulation and gene expression, with implications for various biological processes and diseases.The GTF2E2 Polyclonal Antibody (CAB8732) provides researchers with a reliable tool for studying the functions and regulation of GTF2E2 in different cellular contexts. By investigating the role of GTF2E2 in transcriptional processes, researchers can gain insights into gene regulation mechanisms and potentially identify new therapeutic targets for diseases related to aberrant gene expression.
Product Name:
GTF2E2 Rabbit Polyclonal Antibody
SKU:
CAB8732
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-291 of human GTF2E2 (NP_002086.1).
The general transcription factor IIE (TFIIE) is part of the RNA polymerase II transcription initiation complex, recruiting TFIIH and being essential for promoter clearance by RNA polymerase II. TFIIE is a heterodimer (and sometimes heterotetramer) of alpha and beta subunits. The protein encoded by this gene represents the beta subunit of TFIIE.
Purification Method:
Affinity purification
Gene ID:
2961
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using GTF2E2 antibody (CAB8732) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
