The GTF2E1 Polyclonal Antibody (CAB15275) is specifically designed for research involving GTF2E1, a key transcription factor that plays a crucial role in gene regulation and transcription initiation. This antibody, produced in rabbits, is highly reactive with human samples and has been validated for use in Western blot applications. It specifically binds to the GTF2E1 protein, allowing for the detection and analysis of GTF2E1 expression in various cell types.GTF2E1 is essential for the initiation of transcription by RNA polymerase II, making it a critical factor in gene regulation and expression. Its role in regulating gene transcription makes it an important target for research in fields such as molecular biology, genetics, and cancer research.
Understanding the function and activity of GTF2E1 can provide valuable insights into the mechanisms underlying gene expression and may lead to the development of novel therapeutic strategies targeting transcriptional dysregulation in diseases like cancer.Overall, the GTF2E1 Polyclonal Antibody (CAB15275) is a powerful tool for researchers studying gene regulation, transcription initiation, and the role of GTF2E1 in various biological processes. Its high specificity and reactivity make it ideal for use in a wide range of research applications, providing valuable information for studies aiming to uncover the molecular mechanisms controlling gene expression.
Product Name:
GTF2E1 Rabbit Polyclonal Antibody
SKU:
CAB15275
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 230-439 of human GTF2E1 (NP_005504.2).
Enables RNA polymerase II general transcription initiation factor activity. Involved in transcription by RNA polymerase II. Located in cytosol and nucleoplasm. Part of transcription factor TFIID complex and transcription preinitiation complex.
Purification Method:
Affinity purification
Gene ID:
2960
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using GTF2E1 Rabbit pAb (CAB15275) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5S.
