The GTF2B Polyclonal Antibody (CAB1708) is a powerful tool for research into GTF2B, a key protein involved in transcription initiation. This antibody, produced in rabbit hosts, exhibits high reactivity with human samples and has been validated for use in Western blot applications. Specifically binding to the GTF2B protein, it enables precise detection and analysis in various cell types, making it an ideal choice for studies in molecular biology and gene regulation.GTF2B is a critical component of the transcription machinery, playing a vital role in the initiation of RNA synthesis.
Understanding its function and regulation is essential for unraveling the complexities of gene expression and transcriptional control. The GTF2B Polyclonal Antibody provides researchers with a valuable tool for investigating these processes and gaining insights into various biological pathways, making it a valuable asset in the fields of genetics and biochemistry.
Product Name:
GTF2B Rabbit Polyclonal Antibody
SKU:
CAB1708
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 40-154 of GTF2B (NP_001505.1).
This gene encodes the general transcription factor IIB, one of the ubiquitous factors required for transcription initiation by RNA polymerase II. The protein localizes to the nucleus where it forms a complex (the DAB complex) with transcription factors IID and IIA. Transcription factor IIB serves as a bridge between IID, the factor which initially recognizes the promoter sequence, and RNA polymerase II.
Purification Method:
Affinity purification
Gene ID:
2959
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using GTF2B Rabbit pAb (CAB1708) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 180s.
