The GSTZ1 Polyclonal Antibody (CAB6129) is a vital tool for researchers studying GSTZ1, an enzyme involved in the detoxification of xenobiotics and metabolism of tyrosine. This antibody, produced in rabbits, shows a strong reactivity with human samples and is recommended for Western blotting applications. By specifically binding to the GSTZ1 protein, this antibody allows for accurate detection and analysis in a variety of cell types, making it an essential component in studies focused on toxicology, metabolism, and liver function.
GSTZ1 plays a crucial role in the breakdown of various toxic compounds and is implicated in the development of certain diseases, such as metabolic disorders and cancer. Understanding the function and regulation of GSTZ1 is essential for unraveling its role in disease pathogenesis and identifying potential therapeutic targets. The GSTZ1 Polyclonal Antibody is a valuable tool for researchers seeking to further elucidate the biological functions of GSTZ1 and its implications in health and disease.
Product Name:
GSTZ1 Rabbit Polyclonal Antibody
SKU:
CAB6129
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-216 of human GSTZ1 (NP_665877.1).
This gene is a member of the glutathione S-transferase (GSTs) super-family which encodes multifunctional enzymes important in the detoxification of electrophilic molecules, including carcinogens, mutagens, and several therapeutic drugs, by conjugation with glutathione. This enzyme catalyzes the conversion of maleylacetoacetate to fumarylacetoacatate, which is one of the steps in the phenylalanine/tyrosine degradation pathway. Deficiency of a similar gene in mouse causes oxidative stress. Several transcript variants of this gene encode multiple protein isoforms.
Purification Method:
Affinity purification
Gene ID:
2954
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using GSTZ1 antibody (CAB6129) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
