The GSTT2 Polyclonal Antibody (CAB15678) is a valuable tool for researchers studying GSTT2, a key enzyme involved in the detoxification of xenobiotics and oxidative stress. This antibody, produced in rabbits, demonstrates high reactivity with human samples and is suitable for use in Western blot applications. By specifically binding to the GSTT2 protein, this antibody enables precise detection and analysis in various cell types, making it an essential reagent for studies in toxicology, pharmacology, and cancer research.GSTT2 is a member of the glutathione S-transferase family, which plays a crucial role in cellular defense against harmful compounds by catalyzing the conjugation of glutathione to xenobiotics.
Its involvement in detoxification pathways makes GSTT2 a target of interest for investigating drug metabolism, environmental toxin exposure, and carcinogenesis. Understanding the function and regulation of GSTT2 is essential for developing strategies to enhance detoxification mechanisms and prevent adverse effects associated with toxic exposures.
Product Name:
GSTT2 Rabbit Polyclonal Antibody
SKU:
CAB15678
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-244 of human GSTT2 (NP_000845.2).
The protein encoded by this gene, glutathione S-transferase (GST) theta 2 (GSTT2), is a member of a superfamily of proteins that catalyze the conjugation of reduced glutathione to a variety of electrophilic and hydrophobic compounds. Human GSTs can be divided into five main classes: alpha, mu, pi, theta, and zeta. The theta class includes GSTT1, GSTT2, and GSTT2B. GSTT2 and GSTT2B are nearly identical to each other, and share 55% amino acid identity with GSTT1. All three genes may play a role in human carcinogenesis. The GSTT2 gene is a pseudogene in some populations.
Purification Method:
Affinity purification
Gene ID:
2953
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using GSTT2 Rabbit pAb (CAB15678) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.
