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GSTT2 Monoclonal Antibody [PAT10H4AT] (CPAB0218)

SKU:
CPAB0218
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Host Species:
Mouse
Isotype:
IgG2b 
Clone:
PAT10H4AT
Applications:
ELISA
FC
€149
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Description

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GSTT2 Monoclonal Antibody [PAT10H4AT] (CPAB0218)

The GSTT2 Polyclonal Antibody (CPAB0218) is a powerful tool for research involving the GSTT2 enzyme, an important player in drug metabolism and detoxification processes in the body. This antibody, raised in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By binding to the GSTT2 protein, this antibody enables accurate detection and analysis in various cell types, making it an invaluable asset for studies in pharmacology, toxicology, and personalized medicine.GSTT2, a member of the glutathione S-transferase family, is involved in the conjugation of glutathione to a wide range of xenobiotics, drugs, and carcinogens, aiding in their elimination from the body.

Understanding the expression and function of GSTT2 is essential for predicting individual responses to medications and environmental toxins, as well as for developing strategies to enhance detoxification processes in patients with impaired enzyme activity. Research on GSTT2 may also provide insights into the mechanisms of drug resistance and susceptibility to chemical-induced toxicity, offering new avenues for therapeutic interventions and precision medicine approaches.

Product Name:GSTT2 Antibody
Product Sku:CPAB0218
Size:5μg
Host Species:Mouse
Immunogen:Anti-human GSTT2 mAb, clone PAT1H4AT, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human GSTT2 protein 1-244 amino acids purified from Ecoli.
Clone:PAT10H4AT.
Reactivity:Human
Applications:ELISA, Flow Cytometry
Purification Method:GSTT2 antibody was purified from mouse ascitic fluids by protein-A affinity chromatography.
Isotype:IgG2b 
Background:GSTT2 belongs to the glutathione s-transferase (GST) family of proteins. There are eight GST proteins families, named alpha, kappa, mu, omega, pi, sigma, theta and zeta. Each one of the GST families has several proteins with different functions throughout the cell. The theta type members GSTT1 and GSTT2 have a 55% aa sequence homology and hold a vital role in human carcinogenesis. The theta genes are structurally similar €“ each has five exons with identical exon/intron boundaries.
Synonyms:Glutathione S-transferase theta 2, GST class-theta-2, GSTT2B, Glutathione S-transferase theta-2B, EC 2.5.1.18.
Storage Buffer:For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.

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