The GSTT1 Monoclonal Antibody is a cutting-edge research tool designed for studying the glutathione S-transferase theta 1 (GSTT1) enzyme, which plays a key role in detoxification processes within the body. This antibody, produced using state-of-the-art technology, specifically targets the GSTT1 protein and is highly sensitive and specific in detecting its presence in human samples.GSTT1 is a crucial enzyme involved in the metabolism and elimination of various toxins and carcinogens, making it a target of interest in research on drug metabolism, environmental toxicology, and cancer biology. This monoclonal antibody allows for the precise detection and quantification of GSTT1 levels in different cell types, tissues, and biological samples, making it an invaluable tool for understanding the mechanisms of detoxification and their implications in health and disease.
With its high specificity and reliability in experimental settings, the GSTT1 Monoclonal Antibody is ideal for use in Western blot assays, immunohistochemistry, and other molecular biology techniques. Researchers in the fields of biochemistry, pharmacology, and toxicology will find this antibody essential for unraveling the role of GSTT1 in various physiological and pathological processes, paving the way for new insights and potential therapeutic strategies.
The protein encoded by this gene, glutathione S-transferase (GST) theta 1 (GSTT1), is a member of a superfamily of proteins that catalyze the conjugation of reduced glutathione to a variety of electrophilic and hydrophobic compounds. Human GSTs can be divided into five main classes: alpha, mu, pi, theta, and zeta. The theta class includes GSTT1, GSTT2, and GSTT2B. GSTT1 and GSTT2/GSTT2B share 55% amino acid sequence identity and may play a role in human carcinogenesis. The GSTT1 gene is haplotype-specific and is absent from 38% of the population. Alternative splicing of this gene results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
2952
Clone Number:
ARC59201
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates, using GSTT1 antibody (CAB23070) at 1:2000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
