The GSTP1 Polyclonal Antibody (CAB5691) is a valuable tool for researchers studying GSTP1, a key enzyme involved in detoxification and drug metabolism processes in the body. This antibody, produced in rabbits, has high specificity and sensitivity for detecting GSTP1 in human samples, making it ideal for use in Western blot applications. By selectively binding to the GSTP1 protein, this antibody allows for precise detection and analysis of GSTP1 expression in various cell types, facilitating research in fields such as toxicology, pharmacology, and cancer biology.GSTP1, a member of the glutathione S-transferase family, plays a crucial role in protecting cells against oxidative stress and harmful chemicals by conjugating them with glutathione for detoxification.
Dysregulation of GSTP1 expression has been implicated in various diseases, including cancer, neurodegenerative disorders, and drug resistance. Studying the function and regulation of GSTP1 is essential for developing strategies to modulate its activity for therapeutic purposes.Overall, the GSTP1 Polyclonal Antibody (CAB5691) is a reliable tool for researchers aiming to investigate the role of GSTP1 in health and disease, providing valuable insights into its molecular mechanisms and potential therapeutic applications.
Product Name:
GST3/GSTP1 Rabbit Polyclonal Antibody
SKU:
CAB5691
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-210 of human GST3/GST3/GSTP1 (NP_000843.1).
Glutathione S-transferases (GSTs) are a family of enzymes that play an important role in detoxification by catalyzing the conjugation of many hydrophobic and electrophilic compounds with reduced glutathione. Based on their biochemical, immunologic, and structural properties, the soluble GSTs are categorized into 4 main classes: alpha, mu, pi, and theta. This GST family member is a polymorphic gene encoding active, functionally different GSTP1 variant proteins that are thought to function in xenobiotic metabolism and play a role in susceptibility to cancer, and other diseases.
Purification Method:
Affinity purification
Gene ID:
2950
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using GST3/GSTP1 Rabbit pAb (CAB5691) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.
