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GSTP1 Monoclonal Antibody [PAT12C10AT] (CPAB0272)

SKU:
CPAB0272
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Host Species:
Mouse
Isotype:
IgG1
Clone:
PAT12C10AT
Applications:
WB
ELISA
FC
€149
Frequently bought together:

Description

system_update_alt Datasheet

GSTP1 Monoclonal Antibody [PAT12C10AT] (CPAB0272)

The GSTP1 Antibody (CPAB0272) is specifically designed for research involving Glutathione S-transferase Pi 1 (GSTP1), an enzyme involved in detoxification processes within the cell. Raised in rabbits, this polyclonal antibody is highly reactive with human samples and has been validated for use in Western blot applications. By binding to the GSTP1 protein, this antibody enables the detection and analysis of GSTP1 in a variety of cell types, making it an essential tool for studies in toxicology, pharmacology, and cancer research.GSTP1 plays a crucial role in protecting cells from oxidative stress and carcinogens by catalyzing the conjugation of glutathione to various xenobiotics.

Understanding the function and regulation of GSTP1 is essential for elucidating its role in drug metabolism, environmental toxin exposure, and the development of cancer. The GSTP1 Antibody offers researchers a reliable tool for investigating the expression and activity of GSTP1 in various biological processes, paving the way for new insights into cellular detoxification mechanisms.

Product Name:GSTP1 Antibody
Product Sku:CPAB0272
Size:5μg
Host Species:Mouse
Immunogen:Anti-human GSTP1 mAb, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with recombinant human GSTP1 amino acids 1-21 purified from Ecoli.
Clone:PAT12C10AT
Reactivity:Human
Applications:Western Blot, ELISA, Flow Cytometry
Purification Method:GSTP1 antibody was purified from mouse ascitic fluids by protein-A affinity chromatography.
Isotype:IgG1
Background:GSTP1 is a polymorphic gene encoding active, functionally different GSTP1 variant proteins that are believed to function in xenobiotic metabolism and have a part in susceptibility to cancer, and other diseases. GSTP1 is a glutathione S-transferase belonging to the pi class. GST family enzymes play a significant role in detoxification by catalyzing the conjugation of many hydrophobic and electrophilic compounds with reduced glutathione. Based upon the biochemical, immunologic and structural properties of the soluble GSTs they are grouped into 4 main classes: alpha, mu, pi, and theta. The GSTP1 enzyme acts by catalyzing the reaction of glutathione with an acceptor molecule to form a Sulfur-substituted glutathione. The reactions employing glutathione contribute the transformation of a broad range of electrophiles, including reactive products of lipid, protein, carcinogens, therapeutic drugs, environmental toxins, and products of oxidative stress.
Synonyms:Glutathione S-transferase P 1, Gst P1, GST YF-YF, GST class-pi, GST-piB, Preadipocyte growth factor.
Storage Buffer:For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.

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