GSTM2 Rabbit Polyclonal Antibody (CAB13496)
- SKU:
- CAB13496
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
Product Name: | GSTM2 Rabbit Polyclonal Antibody |
SKU: | CAB13496 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-218 of human GSTM2 (NP_000839.1). |
Sequence: | MPMT LGYW NIRG LAHS IRLL LEYT DSSY EEKK YTMG DAPD YDRS QWLN EKFK LGLD FPNL PYLI DGTH KITQ SNAI LRYI ARKH NLCG ESEK EQIR EDIL ENQF MDSR MQLA KLCY DPDF EKLK PEYL QALP EMLK LYSQ FLGK QPWF LGDK ITFV DFIA YDVL ERNQ VFEP SCLD AFPN LKDF ISRF EGLE KISA YMKS SRFL PRPV FTKM AVWG NK |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | GST4; GSTM; GTHMUS; GSTM2-2; GSTM2 |
Positive Sample: | Mouse testis |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm. |
Calculated MW: | 26kDa |
Observed MW: | 27kDa |
Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs.
Purification Method: | Affinity purification |
Gene ID: | 2946 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |