The GSTK1 Polyclonal Antibody (CAB5226) is a powerful tool for researchers studying GSTK1, an enzyme involved in glutathione metabolism and detoxification pathways. This antibody, generated in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By targeting the GSTK1 protein, researchers can investigate its expression levels and activity in different cell types, making it ideal for research in areas such as toxicology, oxidative stress, and cancer biology.
GSTK1 is a crucial player in protecting cells from oxidative damage by facilitating the conjugation of glutathione to xenobiotics and reactive oxygen species. Its role in detoxification pathways renders it a promising target for understanding drug metabolism, environmental toxin exposure, and disease processes. Studies on GSTK1 can provide insights into how cells combat oxidative stress and maintain cellular homeostasis, offering potential therapeutic avenues for diseases related to oxidative damage.
Product Name:
GSTK1 Rabbit Polyclonal Antibody
SKU:
CAB5226
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-226 of human GSTK1 (NP_057001.1).
This gene encodes a member of the kappa class of the glutathione transferase superfamily of enzymes that function in cellular detoxification. The encoded protein is localized to the peroxisome and catalyzes the conjugation of glutathione to a wide range of hydrophobic substates facilitating the removal of these compounds from cells. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
373156
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using GSTK1 Rabbit pAb (CAB5226) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
