The GST3/GSTP1 Rabbit Monoclonal Antibody (CAB19061) is a crucial tool for researchers studying glutathione S-transferase omega-3 (GST3) and glutathione S-transferase pi 1 (GSTP1) proteins in various biological processes. This antibody, generated in rabbits, shows high reactivity with human samples and is validated for use in Western blot applications.GST3 and GSTP1 are enzymes involved in the detoxification of electrophilic compounds and oxidative stress response. They play important roles in protecting cells from damage and maintaining cellular homeostasis. The GST3/GSTP1 Rabbit Monoclonal Antibody binds specifically to these proteins, allowing for their detection and analysis in a variety of cell types.
Research into GST3 and GSTP1 has shown their implications in cancer development, drug resistance, and oxidative stress-related diseases. By understanding the functions and regulation of these enzymes, researchers can gain valuable insights into potential therapeutic targets for cancer and other diseases. The GST3/GSTP1 Rabbit Monoclonal Antibody provides a valuable tool for studying these proteins and their roles in various biological processes.
Product Name:
GST3/GSTP1 Rabbit Monoclonal Antibody
SKU:
CAB19061
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 100-201 of human GST3/GSTP1 (P09211).
Glutathione S-transferases (GSTs) are a family of enzymes that play an important role in detoxification by catalyzing the conjugation of many hydrophobic and electrophilic compounds with reduced glutathione. Based on their biochemical, immunologic, and structural properties, the soluble GSTs are categorized into 4 main classes: alpha, mu, pi, and theta. This GST family member is a polymorphic gene encoding active, functionally different GSTP1 variant proteins that are thought to function in xenobiotic metabolism and play a role in susceptibility to cancer, and other diseases.
Purification Method:
Affinity purification
Gene ID:
2950
Clone Number:
ARC0439
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using GST3/GSTP1 antibody (CAB19061) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3min.
