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Glutathione Synthetase (GSS) Rabbit Polyclonal Antibody (CAB1069)

SKU:
CAB1069
Product Type:
Antibody
Reactivity:
Human
Mouse
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Metabolism
  • Metabolism Antibodies 1 Anti-GSS Antibody CAB1069
  • Metabolism Antibodies 1 Anti-GSS Antibody CAB1069
€139 - €419
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Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:Glutathione Synthetase (GSS) Rabbit Polyclonal Antibody
SKU:CAB1069
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse,Rat
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 250-474 of human Glutathione Synthetase (GSS) (NP_000169.1).
Sequence:QDRR LFVD GQEI AVVY FRDG YMPR QYSL QNWE ARLL LERS HAAK CPDI ATQL AGTK KVQQ ELSR PGML EMLL PGQP EAVA RLRA TFAG LYSL DVGE EGDQ AIAE ALAA PSRF VLKP QREG GGNN LYGE EMVQ ALKQ LKDS EERA SYIL MEKI EPEP FENC LLRP GSPA RVVQ CISE LGIF GVYV RQEK TLVM NKHV GHLL RTKA IEHA DGGV AAGV AVLD NPYP V
Tested Applications:WB IF/ICC ELISA
Recommended Dilution:WB,1:500 - 1:1000 IF/ICC,1:50 - 1:200
Synonyms:GSHS; HEL-S-64p; HEL-S-88n; Glutathione Synthetase (GSS)
Positive Sample:DU145,SW480,K-562,BT-474,22Rv1,Raji,Mouse kidney,Mouse liver,Mouse lung
Conjugate:Unconjugated
Cellular Localization:cytosol, extracellular exosome
Calculated MW:52kDa
Observed MW:53kDa

Glutathione is important for a variety of biological functions, including protection of cells from oxidative damage by free radicals, detoxification of xenobiotics, and membrane transport. The protein encoded by this gene functions as a homodimer to catalyze the second step of glutathione biosynthesis, which is the ATP-dependent conversion of gamma-L-glutamyl-L-cysteine to glutathione. Defects in this gene are a cause of glutathione synthetase deficiency.

Purification Method:Affinity purification
Gene ID:2937
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Product ImageWestern blot analysis of extracts of various cell lines, using Glutathione Synthetase (Glutathione Synthetase (GSS)) antibody (CAB1069) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.

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