GSR Rabbit Polyclonal Antibody (CAB12070)
- SKU:
- CAB12070
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | GSR Rabbit Polyclonal Antibody |
SKU: | CAB12070 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 273-522 of human GSR (NP_000628.2). |
Sequence: | MIST NCTE ELEN AGVE VLKF SQVK EVKK TLSG LEVS MVTA VPGR LPVM TMIP DVDC LLWA IGRV PNTK DLSL NKLG IQTD DKGH IIVD EFQN TNVK GIYA VGDV CGKA LLTP VAIA AGRK LAHR LFEY KEDS KLDY NNIP TVVF SHPP IGTV GLTE DEAI HKYG IENV KTYS TSFT PMYH AVTK RKTK CVMK MVCA NKEE KVVG IHMQ GLGC DEML QGFA VAVK MGAT KADF DNTV AIHP TSSE ELVT LR |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | GR; GSRD; HEL-75; HEL-S-122m; GSR |
Positive Sample: | LO2,HeLa,A-549,Jurkat,Mouse brain,Mouse heart,Mouse kidney |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Mitochondrion. |
Calculated MW: | 56kDa |
Observed MW: | 55kDa |
This gene encodes a member of the class-I pyridine nucleotide-disulfide oxidoreductase family. This enzyme is a homodimeric flavoprotein. It is a central enzyme of cellular antioxidant defense, and reduces oxidized glutathione disulfide (GSSG) to the sulfhydryl form GSH, which is an important cellular antioxidant. Rare mutations in this gene result in hereditary glutathione reductase deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been found.
Purification Method: | Affinity purification |
Gene ID: | 2936 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |