The GSPT1 Polyclonal Antibody (CAB16214) is a valuable tool for researchers studying GSPT1, a protein involved in translation termination in eukaryotes. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot and immunohistochemistry applications. By binding to GSPT1, this antibody allows for the detection and analysis of the protein in various cell types, making it ideal for studies in molecular biology and translational research.
GSPT1, also known as eRF3a, is essential for the accurate termination of protein synthesis and plays a crucial role in maintaining cellular homeostasis. Dysregulation of GSPT1 has been linked to a variety of diseases, including cancer and neurodegenerative disorders. Understanding the function of GSPT1 is key to developing targeted therapies for these conditions, making the GSPT1 Polyclonal Antibody a valuable resource for researchers in the field.
Product Name:
GSPT1 Rabbit Polyclonal Antibody
SKU:
CAB16214
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 138-420 of human GSPT1 (NP_001123478.1).
Enables translation release factor activity. Involved in regulation of translational termination. Acts upstream of or within protein methylation. Predicted to be located in cytosol. Predicted to be part of translation release factor complex.
Purification Method:
Affinity purification
Gene ID:
2935
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates, using GSPT1 Rabbit pAb (CAB16214) at 1:2000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
