The GSN Rabbit Polyclonal Antibody (CAB16869) is a valuable tool for researchers studying GSN, a protein involved in actin filament assembly and disassembly. Raised in rabbits, this antibody is highly specific and reactive with human samples, making it ideal for use in Western blot applications. By binding to GSN, the antibody enables the detection and analysis of this important protein in various cell types.GSN, also known as gelsolin, is a key regulator of actin dynamics and is involved in a wide range of cellular processes, including cell motility, cytokinesis, and apoptosis. Dysregulation of GSN expression has been implicated in a variety of diseases, including cancer, neurodegenerative disorders, and autoimmune diseases.
Therefore, understanding the role of GSN in these conditions is essential for the development of targeted therapies and potential diagnostic tools.Overall, the GSN Rabbit Polyclonal Antibody (CAB16869) is a valuable resource for researchers interested in exploring the function of GSN and its potential implications in disease development and progression. Its high specificity and sensitivity make it a reliable tool for studying this important protein in a research setting.
Product Name:
Gelsolin Rabbit Polyclonal Antibody
SKU:
CAB16869
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 282-438 of human Gelsolin (NP_000168.1).
The protein encoded by this gene binds to the "plus" ends of actin monomers and filaments to prevent monomer exchange. The encoded calcium-regulated protein functions in both assembly and disassembly of actin filaments. Defects in this gene are a cause of familial amyloidosis Finnish type (FAF). Multiple transcript variants encoding several different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
2934
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using Gelsolin Rabbit pAb (CAB16869) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
