[KO Validated] GSK3β Rabbit Polyclonal Antibody (CAB6164)
- SKU:
- CAB6164
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
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Description
Product Name: | [KO Validated] GSK3β Rabbit Polyclonal Antibody |
SKU: | CAB6164 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 320-420 of human GSK3β (NP_001139628.1). |
Sequence: | LLEY TPTA RLTP LEAC AHSF FDEL RDPN VKLP NGRD TPAL FNFT TQEL SSNP PLAT ILIP PHAR IQAA ASTP TNAT AASD ANTG DRGQ TNNA ASAS ASNS T |
Tested Applications: | WB IF/ICC IP ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IP,0.5μg-4μg antibody for 200μg-400μg extracts of whole cellsIF/ICC,1:50 - 1:200 |
Synonyms: | GSK3B; gsk-3β; GSK3β |
Positive Sample: | LO2,HeLa,22Rv1,U-251MG |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Cytoplasm, Nucleus. |
Calculated MW: | 47kDa |
Observed MW: | 46kDa |
The protein encoded by this gene is a serine-threonine kinase belonging to the glycogen synthase kinase subfamily. It is a negative regulator of glucose homeostasis and is involved in energy metabolism, inflammation, ER-stress, mitochondrial dysfunction, and apoptotic pathways. Defects in this gene have been associated with Parkinson disease and Alzheimer disease.
Purification Method: | Affinity purification |
Gene ID: | 2932 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |