The GSK3A Polyclonal Antibody (CAB0645) is a valuable tool for researchers studying GSK3A, a key enzyme involved in various cellular processes such as cell growth, differentiation, and proliferation. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By binding to the GSK3A protein, this antibody enables accurate detection and analysis in a wide range of cell types, making it ideal for investigations in cell biology and cancer research.
GSK3A, also known as glycogen synthase kinase 3 alpha, is a crucial player in signaling pathways that regulate cell survival, gene expression, and metabolism. Dysregulation of GSK3A activity has been implicated in numerous diseases, including cancer, diabetes, and neurodegenerative disorders. Therefore, studying the function of GSK3A using this highly specific antibody could provide insights into potential therapeutic targets for these conditions.
Product Name:
GSK3α Rabbit Polyclonal Antibody
SKU:
CAB0645
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 409-483 of human GSK3α (NP_063937.2).
This gene encodes a multifunctional Ser/Thr protein kinase that is implicated in the control of several regulatory proteins including glycogen synthase, and transcription factors, such as JUN. It also plays a role in the WNT and PI3K signaling pathways, as well as regulates the production of beta-amyloid peptides associated with Alzheimer's disease.
Purification Method:
Affinity purification
Gene ID:
2931
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using GSK3α antibody (CAB0645) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
