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GSK3β Polyclonal Antibody

SKU:
CAB21444
Product Type:
Antibody
Antibody Type:
Polyclonal Antibody
Reactivity:
Human
Rat
Host Species:
Rabbit
Isotype:
IgG
Applications:
WB
€129 - €359
Frequently bought together:

Description

Product Name:GSK3β Polyclonal Antibody
Product Code:CAB21444
Reactivity:Human, Rat
Applications:Western blotting
Host Species:Rabbit
Purification Method:Affinity purification
Isotype:IgG
Reactivity:Human, Rat
Tested Applications:WB, ELISA
Key Applications:Western blotting
Recommended Dilution:WB 1:500-1:1000
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3.
Positive Samples:293T, C6
Cellular Location:Cell membrane, Cytoplasm, Nucleus

The protein encoded by this gene is a serine-threonine kinase belonging to the glycogen synthase kinase subfamily. It is a negative regulator of glucose homeostasis and is involved in energy metabolism, inflammation, ER-stress, mitochondrial dysfunction, and apoptotic pathways. Defects in this gene have been associated with Parkinson disease and Alzheimer disease.

Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 350-420 of GSK3β (NP_001139628.1).
Sequence:LPNGR DTPAL FNFTT QELSS NPPLA TILIP PHARI QAAAS TPTNA TAASD ANTGD RGQTN NAASA SASNS T
Synonyms:GSK3B, glycogen synthase kinase-3 beta
Calculated MW:47kDa
Observed MW:47kDa

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