The GSG1L Polyclonal Antibody (PAC060124) is a crucial tool for researchers studying the GSG1L protein, which is involved in synaptic transmission and neuronal development. This antibody, generated in rabbits, is highly specific to GSG1L and is validated for use in Western blot and immunofluorescence applications. It binds to the GSG1L protein, allowing for accurate detection and analysis in various cell types, making it an essential reagent for studies in neuroscience and neurodevelopmental disorders.GSG1L is a member of the GSG family and plays a critical role in the formation and function of synapses in the brain.
Its function in synaptic transmission suggests its importance in neurological processes such as learning, memory, and cognition. Research on GSG1L is essential for understanding neurodevelopmental disorders such as autism and schizophrenia, where synaptic dysfunction is implicated. By investigating the role of GSG1L, researchers can uncover potential therapeutic targets for these disorders and advance our understanding of brain development and function.
Antibody Name:
GSG1L Antibody (PACO60124)
Antibody SKU:
PACO60124
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, IF
Recommended Dilutions:
ELISA:1:2000-1:10000, IF:1:50-1:200
Species Reactivity:
Human
Immunogen:
Recombinant Human Germ cell-specific gene 1-like protein (84-176AA)
Immunofluorescence staining of A549 cells with PACO60124 at 1:66, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
Background:
As a component of the inner core of AMPAR complex, modifies AMPA receptor (AMPAR) gating.
Synonyms:
Germ cell-specific gene 1-like protein (GSG1-like protein), GSG1L
UniProt Protein Function:
GSG1L: Belongs to the GSG1 family. 4 isoforms of the human protein are produced by alternative splicing.Protein type: Membrane protein, integral; Membrane protein, multi-passChromosomal Location of Human Ortholog: 16p12.1Molecular Function: protein binding
