The GSDMD Polyclonal Antibody (CAB17308) is a valuable tool for researchers studying gasdermin D (GSDMD), a key protein involved in pyroptosis, a form of inflammatory cell death. This antibody, produced in rabbits, is highly specific to GSDMD and has been validated for use in various applications, including Western blotting.GSDMD is known for its role in promoting inflammation and immune responses by forming pores in cell membranes, leading to cell death and the release of pro-inflammatory signals. Research into GSDMD is important for understanding how the immune system responds to infection, inflammation, and cancer.
The GSDMD Polyclonal Antibody is ideal for detecting GSDMD protein levels in different cell types and tissues, making it a valuable tool for studies in immunology, cell biology, and inflammation research. By targeting GSDMD, researchers can gain insights into the mechanisms underlying inflammatory responses and develop potential therapeutic interventions for inflammatory diseases.
Gasdermin D is a member of the gasdermin family. Members of this family appear to play a role in regulation of epithelial proliferation. Gasdermin D has been suggested to act as a tumor suppressor. Alternatively spliced transcript variants have been described.
Purification Method:
Affinity purification
Gene ID:
79792
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of various lysates using GSDMD Rabbit pAb (CAB17308) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
