The GSDMC3 Polyclonal Antibody (CAB16741) is a valuable tool for researchers studying GSDMC3, a protein that plays a crucial role in cell death pathways. This antibody, generated in rabbits, has high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to the GSDMC3 protein, this antibody allows for the detection and analysis of GSDMC3 in a variety of cell types, making it an excellent choice for studies in cell biology, apoptosis, and cancer research.GSDMC3, also known as Gasdermin C3, is involved in programmed cell death processes, including pyroptosis and apoptosis.
Dysregulation of GSDMC3 has been implicated in various diseases, such as cancer, inflammatory disorders, and immune-related conditions. By understanding the function of GSDMC3, researchers can gain insights into the mechanisms of cell death and potential therapeutic targets for these diseases. The GSDMC3 Polyclonal Antibody is a valuable tool for further investigating the role of GSDMC3 in health and disease.
Product Name:
Gsdmc3 Polyclonal Antibody
SKU:
CAB16741
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 2-80 of mouse Gsdmc3 (NP_899017.2).
Predicted to enable phosphatidylinositol-4,5-bisphosphate binding activity; phosphatidylinositol-4-phosphate binding activity; and phosphatidylserine binding activity. Predicted to be involved in defense response to bacterium and pyroptosis. Predicted to act upstream of or within programmed cell death. Predicted to be located in cytoplasm. Is expressed in gut and metanephros. Orthologous to human GSDMC (gasdermin C).
Purification Method:
Affinity purification
Gene ID:
270328
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using Gsdmc3 Rabbit pAb (CAB16741) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
