The GSDMC Monoclonal Antibody is a vital tool for researchers studying GSDMC, a gasdermin family protein involved in pyroptosis, a form of inflammatory cell death. This monoclonal antibody, produced using hybridoma technology, shows high specificity and sensitivity for detecting GSDMC in various biological samples, including human tissue samples.GSDMC plays a crucial role in inflammatory responses and is implicated in multiple diseases, including cancer and inflammatory disorders. By targeting GSDMC, researchers can gain valuable insights into the mechanisms of pyroptosis and its contribution to disease pathology.
This antibody is validated for use in techniques such as immunohistochemistry and Western blotting, making it a versatile tool for studies in cell biology, immunology, and oncology.Overall, the GSDMC Monoclonal Antibody is a valuable resource for researchers seeking to elucidate the role of GSDMC in health and disease, with potential applications in drug discovery and therapeutic development.
Product Name:
GSDMC Monoclonal Antibody
SKU:
CAB21213
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-150 of human GSDMC (NP_113603.1).
293F transfected with GSDMC,HeLa,RAW264.7,Mouse stomach,Rat stomach
Conjugate:
Unconjugated
Cellular Localization:
Cytoplasm.
Calculated MW:
58kDa
Observed MW:
62kDa
Predicted to enable phosphatidylinositol-4,5-bisphosphate binding activity; phosphatidylinositol-4-phosphate binding activity; and phosphatidylserine binding activity. Predicted to be involved in defense response to bacterium and pyroptosis. Predicted to act upstream of or within intestinal epithelial cell development. Located in cytoplasm.
Purification Method:
Affinity purification
Gene ID:
56169
Clone Number:
ARC52482
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using GSDMC Rabbit mAb (CAB21213) at 1:10000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
