The GSDMC Polyclonal Antibody is a valuable tool for researchers studying the gasdermin C (GSDMC) protein, a member of the gasdermin family involved in pyroptosis, a type of programmed cell death associated with inflammation. This antibody, generated in rabbits, is highly specific to human GSDMC and has been validated for use in various applications, including Western blotting.GSDMC has recently garnered attention for its role in promoting inflammation and immune responses in various diseases, such as cancer and inflammatory disorders. By targeting GSDMC, researchers can gain insight into the mechanisms underlying pyroptosis and its implications for disease progression.
This antibody enables the detection and analysis of GSDMC in different cell types, making it an essential tool for studies in immunology and cancer research.Overall, the GSDMC Polyclonal Antibody offers researchers a reliable means of investigating the functions and significance of GSDMC in various biological processes, with the potential to uncover new therapeutic targets for diseases characterized by dysregulated cell death and inflammation.
Product Name:
GSDMC Rabbit Polyclonal Antibody
SKU:
CAB14550
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-100 of human GSDMC (NP_113603.1).
Predicted to enable phosphatidylinositol-4,5-bisphosphate binding activity; phosphatidylinositol-4-phosphate binding activity; and phosphatidylserine binding activity. Predicted to be involved in defense response to bacterium and pyroptosis. Predicted to act upstream of or within intestinal epithelial cell development. Located in cytoplasm.
Purification Method:
Affinity purification
Gene ID:
56169
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates, using GSDMC Rabbit pAb (CAB14550) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
