The GSDMA Polyclonal Antibody is a valuable tool for research involving the GSDMA protein, a member of the gasdermin family implicated in cellular function and disease. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By binding to the GSDMA protein, this antibody enables detection and analysis in a variety of cell types, making it ideal for studies in cell biology, apoptosis, and cancer research.
GSDMA, also known as gasdermin-A, is involved in various cellular processes, including inflammation, cell death, and tumorigenesis. Its role in the development and progression of cancer, as well as its potential as a therapeutic target, makes it a promising area of study for researchers in the fields of oncology and molecular biology. Investigating the function and regulation of GSDMA can provide valuable insights into disease mechanisms and potential treatment strategies.
Product Name:
Gsdma Polyclonal Antibody
SKU:
CAB10602
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 248-347 of mouse Gsdma (NP_067322.1).
Predicted to enable phosphatidylinositol-4,5-bisphosphate binding activity; phosphatidylinositol-4-phosphate binding activity; and phosphatidylserine binding activity. Predicted to be involved in apoptotic process; defense response to bacterium; and pyroptosis. Predicted to act upstream of or within programmed cell death. Located in cytoplasm. Is expressed in esophagus epithelium; stomach; stomach cardiac region; stomach glandular region; and stomach glandular region mucosa. Orthologous to human GSDMA (gasdermin A).
Purification Method:
Affinity purification
Gene ID:
57911
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from Rat stomach, using GSDMA Rabbit pAb (CAB10602) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
