The GSC2 Polyclonal Antibody (PACO00891) is a vital tool for researchers studying GSC2, a protein known for its involvement in various cellular processes, including cell signaling and gene expression. This highly reactive antibody, produced in rabbits, is specifically designed for use in Western blot applications with human samples.GSC2, also referred to as a critical regulator of cell function, plays a key role in numerous biological pathways, making it an intriguing target for studies in molecular biology and cancer research. By binding to the GSC2 protein, this antibody allows for precise detection and analysis in different cell types, offering valuable insights into the mechanisms underlying cellular function and disease progression.
Understanding the functions and regulatory mechanisms of GSC2 is essential for advancing knowledge in the fields of cell biology and oncology. By exploring the role of GSC2 in specific cellular processes, researchers can uncover potential therapeutic targets for various diseases, ultimately leading to the development of novel treatment strategies in the future.
Antibody Name:
GSC2 Antibody
Antibody SKU:
PACO00891
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
WB:1:500-1:2000
Species Reactivity:
Human, Mouse
Immunogen:
synthesized peptide derived from the C-terminal region of human GSC2.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Synonyms:
GSC2; GSCL; Homeobox protein goosecoid-2; GSC-2; Homeobox protein goosecoid-like; GSC-L
UniProt Protein Function:
May have a role in development. May regulate its own transcription. May bind the bicoid consensus sequence TAATCC.
NCBI Summary:
Goosecoidlike (GSCL), a homeodomain-containing gene, resides in the critical region for VCFS/DGS on 22q11. Velocardiofacial syndrome (VCFS) is a developmental disorder characterized by conotruncal heart defects, craniofacial anomalies, and learning disabilities. VCFS is phenotypically related to DiGeorge syndrome (DGS) and both syndromes are associated with hemizygous 22q11 deletions. Because many of the tissues and structures affected in VCFS/DGS derive from the pharyngeal arches of the developing embryo, it is believed that haploinsufficiency of a gene involved in embryonic development may be responsible for its etiology. The gene is expressed in a limited number of adult tissues, as well as in early human development. [provided by RefSeq, Jul 2008]
