The GRP75 Rabbit Monoclonal Antibody is a highly specific and sensitive tool for research involving GRP75 (Glucose-regulated protein 75), a crucial molecular chaperone involved in protein folding and cell stress response. This antibody, developed using rabbit monoclonal technology, demonstrates exceptional reactivity with human samples and is validated for use in various applications, including immunofluorescence and immunohistochemistry.GRP75 is a key player in maintaining cellular homeostasis and promoting cell survival under stress conditions, making it a promising target for studies in cancer biology, neurodegenerative diseases, and metabolic disorders.
By detecting and analyzing GRP75 expression, researchers can gain valuable insights into its function and potential therapeutic implications in diseases associated with protein misfolding and cellular stress.This GRP75 Rabbit Monoclonal Antibody offers researchers a reliable tool for investigating the role of GRP75 in various cellular processes and disease mechanisms, paving the way for new discoveries and therapeutic interventions in the field of molecular biology and cell biology.
Product Name:
Grp75/MOT/HSPA9 Rabbit Monoclonal Antibody
SKU:
CAB11256
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 580-679 of human Grp75/MOT/HSPA9 (P38646).
This gene encodes a member of the heat shock protein 70 gene family. The encoded protein is primarily localized to the mitochondria but is also found in the endoplasmic reticulum, plasma membrane and cytoplasmic vesicles. This protein is a heat-shock cognate protein. This protein plays a role in cell proliferation, stress response and maintenance of the mitochondria. A pseudogene of this gene is found on chromosome 2.
Purification Method:
Affinity purification
Gene ID:
3313
Clone Number:
ARC0566
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using Grp75/MOT/HSPA9 Rabbit mAb (CAB11256) at 1：1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
