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GroEL Monoclonal Antibody [P2E4AT] (CPAB0284)

SKU:
CPAB0284
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Host Species:
Mouse
Isotype:
IgG1
Clone:
P2E4AT
Applications:
WB
ELISA
IHC
€149
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Description

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GroEL Monoclonal Antibody [P2E4AT] (CPAB0284)

The GroEL Antibody (CPAB0284) is an essential tool for researchers studying the GroEL protein, a molecular chaperone involved in protein folding and assembly. This polyclonal antibody, generated in rabbits, exhibits high specificity and sensitivity towards human samples, making it ideal for Western blotting applications.GroEL, also known as HSP60, is a key player in cellular stress response and is implicated in various diseases, including cancer and neurodegenerative disorders. By targeting the GroEL protein, this antibody enables the detection and analysis of GroEL expression levels in different cell types, facilitating research in molecular biology and disease mechanisms.

With its ability to specifically recognize GroEL, this antibody is a valuable tool for investigating the role of chaperone proteins in protein folding and disease pathology. Its reliability and versatility make it a crucial asset for researchers exploring the complex biology of molecular chaperones and their impact on health and disease.

Product Name:GroEL Antibody
Product Sku:CPAB0284
Size:5μg
Host Species:Mouse
Immunogen:Anti-human GroEL mAb, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with recombinant human GroEL amino acids 1-573 purified from Ecoli.
Clone:P2E4AT.
Reactivity:Human
Applications:Western Blot, ELISA, Immunohistochemistry
Purification Method:GroEL antibody was purified from mouse ascitic fluids by protein-G affinity chromatography.
Isotype:IgG1
Background:GroEL, HSP60 is a chaperonin located in the mitochondria which is responsible for the transportation & refolding of proteins from the cytoplasm directly into the mitochondrial matrix. GroEL is regulated by the HSP10 cochaperonin, which is a single heptameric protein ring having a molecular mass of 10 kDa which form a unique complex with HSP60. HSP10, GroES coordinates the ATPase activity of the HSP60 subunits in order to allow the release of bound polypeptide in a manner that is productive for its correct folding.
Synonyms:CPN60, GROEL, HSP60, HSP65, SPG13, CHA60, GROL, crpA, mopA, 60 kDa heat shock protein mitochondrial, Heat shock protein 60, HSP-60, 60 kDa chaperonin, Chaperonin 60, Mitochondrial matrix protein P1, P60 lymphocyte protein, HuCHA60, HSPD1.
Storage Buffer:For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.

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