The GRM5 Rabbit Monoclonal Antibody (CAB3758) is a cutting-edge tool for researchers studying GRM5, a glutamate receptor involved in various neurological processes. This antibody, produced in rabbits, exhibits high specificity and sensitivity towards GRM5 in human samples, making it a reliable choice for Western blot experiments.GRM5, a member of the metabotropic glutamate receptor family, plays a key role in synaptic transmission and plasticity, making it a promising target for investigating conditions such as neurodegenerative diseases and psychiatric disorders.
By effectively detecting and quantifying GRM5 protein levels in different cell types, this antibody facilitates the study of GRM5 function and dysfunction in various biological contexts.With its high affinity for GRM5, this antibody is an essential tool for researchers aiming to unravel the molecular mechanisms underlying neurological disorders and develop targeted therapies. Its reliable performance in Western blot assays makes it an indispensable resource for advancing our understanding of GRM5 biology and its implications for human health.
Product Name:
GRM5 Rabbit Monoclonal Antibody
SKU:
CAB3758
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1100-1200 of human GRM5 (P41594).
This gene encodes a member of the G-protein coupled receptor 3 protein family. The encoded protein is a metabatropic glutamate receptor, whose signaling activates a phosphatidylinositol-calcium second messenger system. This protein may be involved in the regulation of neural network activity and synaptic plasticity. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. A pseudogene of this gene has been defined on chromosome 11. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
2915
Clone Number:
ARC0250
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of Mouse brain, using GRM5 antibody (CAB3758) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
