GRM5 Rabbit Polyclonal Antibody (CAB9819)
- SKU:
- CAB9819
- Product Type:
- Antibody
- Applications:
- WB
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | GRM5 Rabbit Polyclonal Antibody |
SKU: | CAB9819 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 870-1070 of human GRM5 (NP_001137303.1). |
Sequence: | GSSG ETLR YKDR RLAQ HKSE IECF TPKG SMGN GGRA TMSS SNGK SVTW AQNE KSSR GQHL WQRL SIHI NKKE NPNQ TAVI KPFP KSTE SRGL GAGA GAGG SAGG VGAT GGAG CAGA GPGG PESP DAGP KALY DVAE AEEH FPAP ARPR SPSP ISTL SHRA GSAS RTDD DVPS LHSE PVAR SSSS QGSL MEQI SSVV TRFT A |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IF/ICC,1:50 - 1:200 |
Synonyms: | mGlu5; GPRC1E; MGLUR5; PPP1R86; GRM5 |
Positive Sample: | Mouse brain,Rat brain |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Multi-pass membrane protein. |
Calculated MW: | 132kDa |
Observed MW: | 150kDa/300kDa |
This gene encodes a member of the G-protein coupled receptor 3 protein family. The encoded protein is a metabatropic glutamate receptor, whose signaling activates a phosphatidylinositol-calcium second messenger system. This protein may be involved in the regulation of neural network activity and synaptic plasticity. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. A pseudogene of this gene has been defined on chromosome 11. Alternative splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 2915 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |