The GRK2 Polyclonal Antibody (PAC049270) is a valuable tool for researchers studying G protein-coupled receptor kinase 2 (GRK2) and its role in various cellular processes. This antibody, produced in rabbits, shows high reactivity towards human samples and has been validated for Western blot applications. By binding to the GRK2 protein, it allows for accurate detection and analysis in a variety of cell types, making it ideal for investigations in signal transduction pathways and drug development.GRK2 is a key regulator of G protein-coupled receptor signaling, playing a crucial role in processes such as receptor desensitization and internalization.
Dysregulation of GRK2 has been implicated in various diseases, including cardiovascular disorders, diabetes, and neurodegenerative conditions. Understanding the mechanisms underlying GRK2 function is essential for developing targeted therapies and advancing our knowledge of these pathological conditions.Overall, the GRK2 Polyclonal Antibody offers researchers a reliable tool to study the intricate role of GRK2 in cellular signaling pathways and disease pathogenesis, ultimately paving the way for novel therapeutic interventions.
Antibody Name:
Grk2 Antibody (PACO49270)
Antibody SKU:
PACO49270
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA
Recommended Dilutions:
Species Reactivity:
Mouse
Immunogen:
Recombinant Mouse Beta-adrenergic receptor kinase 1 protein (1-689AA)
Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors, probably inducing a desensitization of them.
