The GRIP1 Polyclonal Antibody (CAB5747) is a valuable tool for researchers studying GRIP1, a protein involved in synaptic transmission and plasticity. This antibody is produced in rabbits and has high reactivity with human samples, making it ideal for Western blot applications. By binding to the GRIP1 protein, this antibody enables the detection and analysis of GRIP1 levels in various cell types, providing insights into its role in neuronal function.GRIP1, also known as glutamate receptor-interacting protein 1, is a key player in the regulation of AMPA receptor trafficking and synaptic strength. Its interactions with various synaptic proteins make it a crucial component of excitatory synapses and synaptic plasticity.
Research on GRIP1 is essential for understanding the mechanisms underlying synaptic transmission and how disruptions in these processes contribute to neurological disorders.This polyclonal antibody is a valuable tool for investigating the function of GRIP1 in neurobiology, neurodevelopment, and neurodegenerative diseases. By studying the role of GRIP1 in synaptic function, researchers can gain valuable insights into the pathophysiology of conditions such as Alzheimer's disease, Parkinson's disease, and schizophrenia. Harnessing the potential of this antibody can lead to groundbreaking discoveries in the field of neuroscience.
Product Name:
GRIP1 Rabbit Polyclonal Antibody
SKU:
CAB5747
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human GRIP1 (NP_001171545.1).
This gene encodes a member of the glutamate receptor interacting protein family. The encoded scaffold protein binds to and mediates the trafficking and membrane organization of a number of transmembrane proteins. Alternatively spliced transcript variants encoding different isoforms have been described.
Purification Method:
Affinity purification
Gene ID:
23426
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of 293T cells, using GRIP1 Antibody (CAB5747) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 60s.
