The Grina Polyclonal Antibody (CAB16380) is a valuable tool for researchers studying Grina, a protein involved in synaptic plasticity and neurotransmission. This antibody, generated in rabbits, exhibits high reactivity with human samples and is validated for use in various applications, including Western blotting. By specifically binding to the Grina protein, this antibody enables accurate detection and analysis in different cell types, making it ideal for investigations in neurobiology and neuroscience research.Grina, also known as the NMDA receptor subunit NR2A, plays a crucial role in excitatory synaptic transmission and plasticity in the brain. Its involvement in regulating synaptic activity makes it a key player in learning and memory processes.
Furthermore, dysregulation of Grina has been implicated in various neurological disorders, including Alzheimer's disease and schizophrenia. Therefore, understanding the function of Grina is essential for developing targeted therapies for these conditions.Overall, the Grina Polyclonal Antibody (CAB16380) serves as a valuable tool for researchers looking to deepen their understanding of the role of Grina in synaptic function and neurological disorders. Its high specificity and sensitivity make it a reliable choice for studies aiming to unravel the complexities of the brain's molecular mechanisms.
Product Name:
GRINA Rabbit Polyclonal Antibody
SKU:
CAB16380
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human GRINA (NP_000828.1).
Predicted to enable transmembrane transporter binding activity. Predicted to act upstream of or within endoplasmic reticulum calcium ion homeostasis and negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway. Predicted to be located in Golgi apparatus and endoplasmic reticulum. Predicted to be integral component of membrane.
Purification Method:
Affinity purification
Gene ID:
2907
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from Mouse pancreas, using GRINA Rabbit pAb (CAB16380) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
