The Grin2D Polyclonal Antibody (CAB10080) is a valuable tool for researchers studying Grin2D, a subunit of the NMDA receptor that plays a critical role in neuronal signaling. This antibody, developed in rabbits, has high reactivity with human samples and has been validated for use in Western blot applications. By targeting the Grin2D protein, this antibody allows for the detection and analysis of Grin2D in various cell types, making it ideal for studies in neuroscience and neurology.Grin2D is essential for mediating excitatory neurotransmission and synaptic plasticity in the brain, making it a key target for research on neurological disorders such as Alzheimer's disease, schizophrenia, and epilepsy.
Understanding the function and regulation of Grin2D is crucial for developing targeted therapies that can modulate NMDA receptor activity and treat these debilitating conditions.Overall, the Grin2D Polyclonal Antibody is a valuable tool for researchers investigating the role of Grin2D in neuronal signaling and brain function. Its high specificity and sensitivity make it an essential component of studies aiming to unravel the complex mechanisms underlying neurological disorders and develop novel therapeutic interventions.
Product Name:
GRIN2D Rabbit Polyclonal Antibody
SKU:
CAB10080
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 330-480 of human GRIN2D (NP_000827.2).
N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate receptors. NMDA channel has been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of the key receptor subunit NMDAR1 (GRIN1) and 1 or more of the 4 NMDAR2 subunits: NMDAR2A (GRIN2A), NMDAR2B (GRIN2B), NMDAR2C (GRIN2C), and NMDAR2D (GRIN2D).
Purification Method:
Affinity purification
Gene ID:
2906
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using GRIN2D antibody (CAB10080) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
