NMDAR2A Rabbit Polyclonal Antibody (CAB0924)
- SKU:
- CAB0924
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Frequently bought together:
Description
Product Name: | NMDAR2A Rabbit Polyclonal Antibody |
SKU: | CAB0924 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1130-1400 of human NMDAR2A (NP_000824.1). |
Sequence: | LDPP QFVE NVTL PENV DFPD PYQD PSEN FRKG DSTL PMNR NPLH NEEG LSNN DQYK LYSK HFTL KDKG SPHS ETSE RYRQ NSTH CRSC LSNM PTYS GHFT MRSP FKCD ACLR MGNL YDID EDQM LQET GNPA TGEQ VYQQ DWAQ NNAL QLQK NKLR ISRQ HSYD NIVD KPRE LDLS RPSR SISL KDRE RLLE GNFY GSLF SVPS SKLS GKKS SLFP QGLE DSKR SKSL LPDH TSDN PFLH SHRD DQRL VIGR CPSD PYKH SLPS QAVN DSY |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IF/ICC,1:50 - 1:200 |
Synonyms: | LKS; EPND; FESD; NR2A; GluN2A; NMDAR2A |
Positive Sample: | Mouse brain,Rat brain |
Conjugate: | Unconjugated |
Cellular Localization: | Cell junction, Cell membrane, Multi-pass membrane protein, postsynaptic cell membrane, synapse. |
Calculated MW: | 165kDa |
Observed MW: | 180kDa |
This gene encodes a member of the glutamate-gated ion channel protein family. The encoded protein is an N-methyl-D-aspartate (NMDA) receptor subunit. NMDA receptors are both ligand-gated and voltage-dependent, and are involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. These receptors are permeable to calcium ions, and activation results in a calcium influx into post-synaptic cells, which results in the activation of several signaling cascades. Disruption of this gene is associated with focal epilepsy and speech disorder with or without cognitive disability. Alternative splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 2903 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |