The GRIK5 Polyclonal Antibody (CAB15676) is a valuable tool for research involving the GRIK5 protein, a subunit of the kainate receptor implicated in neuronal communication and synaptic plasticity. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to the GRIK5 protein, researchers can effectively study its expression and function in various cell types, making it ideal for neuroscience and drug discovery studies.GRIK5, a member of the ionotropic glutamate receptor family, is involved in excitatory neurotransmission and synaptic plasticity, playing a crucial role in learning and memory processes.
Its relevance in neuronal signaling makes it a target for research in neurobiology, neurodegenerative disorders, and psychiatric conditions. Investigating the role of GRIK5 can provide valuable insights into the mechanisms underlying neurological diseases and may lead to the development of novel therapeutic approaches targeting the glutamatergic system.
Product Name:
GRIK5 Rabbit Polyclonal Antibody
SKU:
CAB15676
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 350-420 of human GRIK5 (NP_002079.3).
This gene encodes a protein that belongs to the glutamate-gated ionic channel family. Glutamate functions as the major excitatory neurotransmitter in the central nervous system through activation of ligand-gated ion channels and G protein-coupled membrane receptors. The protein encoded by this gene forms functional heteromeric kainate-preferring ionic channels with the subunits encoded by related gene family members. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
2901
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using GRIK5 Rabbit pAb (CAB15676) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
