GRIK2 Rabbit Polyclonal Antibody (CAB1939)
- SKU:
- CAB1939
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Signal Transduction
Frequently bought together:
Description
Product Name: | GRIK2 Rabbit Polyclonal Antibody |
SKU: | CAB1939 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 30-300 of human GRIK2 (NP_068775.1). |
Sequence: | QGTT HVLR FGGI FEYV ESGP MGAE ELAF RFAV NTIN RNRT LLPN TTLT YDTQ KINL YDSF EASK KACD QLSL GVAA IFGP SHSS SANA VQSI CNAL GVPH IQTR WKHQ VSDN KDSF YVSL YPDF SSLS RAIL DLVQ FFKW KTVT VVYD DSTG LIRL QELI KAPS RYNL RLKI RQLP ADTK DAKP LLKE MKRG KEFH VIFD CSHE MAAG ILKQ ALAM GMMT EYYH YIFT TLDL FALD VEPY RYSG VNMT GFRI LNTE NTQV SSII EKWS MER |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | EAA4; GLR6; MRT6; GLUK6; GLUR6; GluK2; NEDLAS; GRIK2 |
Positive Sample: | SW620,U-251MG |
Conjugate: | Unconjugated |
Cellular Localization: | Cell junction, Cell membrane, Multi-pass membrane protein, postsynaptic cell membrane, synapse. |
Calculated MW: | 103kDa |
Observed MW: | 115kDa |
Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. The subunit encoded by this gene is subject to RNA editing at multiple sites within the first and second transmembrane domains, which is thought to alter the structure and function of the receptor complex. Alternatively spliced transcript variants encoding different isoforms have also been described for this gene. Mutations in this gene have been associated with autosomal recessive cognitive disability.
Purification Method: | Affinity purification |
Gene ID: | 2898 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |