GluR4/GluA4/GRIA4 Rabbit Polyclonal Antibody (CAB1492)
- SKU:
- CAB1492
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Description
Product Name: | GluR4/GluA4/GRIA4 Rabbit Polyclonal Antibody |
SKU: | CAB1492 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 254-433 of human GluR4/GluA4/GluR4/GluA4/GRIA4 (NP_001070712.1). |
Sequence: | HGGA NVTG FQLV DFNT PMVI KLMD RWKK LDQR EYPG SETP PKYT SALT YDGV LVMA ETFR SLRR QKID ISRR GNAG DCLA NPAA PWGQ GIDM ERTL KQVR IQGL TGNV QFDH YGRR VNYT MDVF ELKS TGPR KVGY WNDM DKLV LIQD VPTL GNDT AAIE NRTV VVTT IMPL MKNP ILRN |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:1000 - 1:4000 |
Synonyms: | GLUR4; GLURD; GluA4; GLUR4C; NEDSGA; GluA4-ATD; GluR4/GluA4/GRIA4 |
Positive Sample: | SH-SY5Y,B cells,Mouse brain,Mouse liver,Mouse kidney,Mouse spinal cord,Rat brain |
Conjugate: | Unconjugated |
Cellular Localization: | Cell junction, Cell membrane, Cell projection, Multi-pass membrane protein, dendrite, postsynaptic cell membrane, synapse. |
Calculated MW: | 101kDa |
Observed MW: | 101kDa |
Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes composed of multiple subunits, arranged to form ligand-gated ion channels. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. The subunit encoded by this gene belongs to a family of AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate)-sensitive glutamate receptors, and is subject to RNA editing (AGA->GGA; R->G). Alternative splicing of this gene results in transcript variants encoding different isoforms, which may vary in their signal transduction properties. Some haplotypes of this gene show a positive association with schizophrenia.
Purification Method: | Affinity purification |
Gene ID: | 2893 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |