The GRHL2 Polyclonal Antibody (CAB10153) is a valuable tool for researchers studying the GRHL2 protein, a transcription factor involved in epithelial development and tumor suppression. This antibody, generated in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to the GRHL2 protein, this antibody enables accurate detection and analysis in a variety of cell types, making it an essential component for research in developmental biology, cancer biology, and epithelial tissue function.
GRHL2 is known for its role in regulating epithelial cell differentiation and maintaining tissue integrity, making it a key player in processes like wound healing and barrier function. Additionally, GRHL2 has been implicated in tumor suppression, with studies suggesting its potential as a biomarker for various cancers. By understanding the function and regulation of GRHL2, researchers can gain insights into developmental disorders, cancer progression, and epithelial-related diseases, paving the way for novel therapeutic strategies.
Product Name:
GRHL2 Rabbit Polyclonal Antibody
SKU:
CAB10153
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 80-250 of human GRHL2 (NP_079191.2).
The protein encoded by this gene is a transcription factor that can act as a homodimer or as a heterodimer with either GRHL1 or GRHL3. Defects in this gene are a cause of non-syndromic sensorineural deafness autosomal dominant type 28 (DFNA28).
Purification Method:
Affinity purification
Gene ID:
79977
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using GRHL2 antibody (CAB10153) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
