The GREB1 Polyclonal Antibody (PACO19743) is a valuable tool for researchers studying GREB1, a protein known for its role in hormone-dependent cancers such as breast and prostate cancer. This antibody, generated in rabbits, is highly specific to GREB1 and has been validated for use in various applications including Western blot and immunohistochemistry.GREB1, or growth regulation by estrogen in breast cancer 1, is a key player in the estrogen signaling pathway and has been implicated in the development and progression of hormone-sensitive tumors.
By targeting GREB1, researchers can gain insights into the mechanisms underlying hormone-driven cancers and potentially identify new therapeutic targets.With its high specificity and sensitivity, the GREB1 Polyclonal Antibody is a valuable tool for researchers investigating the role of GREB1 in cancer biology. Its versatility in various applications makes it a valuable asset in research efforts aimed at understanding and targeting hormone-dependent cancers.
Antibody Name:
GREB1 Antibody (PACO19743)
Antibody SKU:
PACO19743
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:5000, IHC:1:50-1:200
Species Reactivity:
Human, Mouse
Immunogen:
Synthetic peptide of human GREB1
Form:
Liquid
Storage Buffer:
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:
Antigen affinity purification
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using PACO19743(GREB1 Antibody) at dilution 1/50, on the right is treated with synthetic peptide. (Original magnification: x200).
The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO19743(GREB1 Antibody) at dilution 1/50, on the right is treated with synthetic peptide. (Original magnification: x200).
Background:
This gene is an estrogen-responsive gene that is an early response gene in the estrogen receptor-regulated pathway. It is thought to play an important role in hormone-responsive tissues and cancer. Three alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
