GRB7 Rabbit Polyclonal Antibody (CAB5690)
- SKU:
- CAB5690
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | GRB7 Rabbit Polyclonal Antibody |
SKU: | CAB5690 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-140 of human GRB7 (NP_001229372.1). |
Sequence: | MELD LSPP HLSS SPED LCPA PGTP PGTP RPPD TPLP EEVK RSQP LLIP TTGR KLRE EERR ATSL PSIP NPFP ELCS PPSQ SPIL GGPS SARG LLPR DASR PHVV KVYS EDGA CRSV EVAA GATA RHVC EMLV QRAH ALSD |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | GRB7 |
Positive Sample: | SKOV3,22Rv1,HeLa |
Conjugate: | Unconjugated |
Cellular Localization: | Cell junction, Cell membrane, Cell projection, Cytoplasm, Cytoplasmic granule, Cytoplasmic side, Peripheral membrane protein, focal adhesion. |
Calculated MW: | 60kDa |
Observed MW: | 60kDa |
The product of this gene belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules. This gene encodes a growth factor receptor-binding protein that interacts with epidermal growth factor receptor (EGFR) and ephrin receptors. The protein plays a role in the integrin signaling pathway and cell migration by binding with focal adhesion kinase (FAK). Several transcript variants encoding two different isoforms have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 2886 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |