The GRB7 Polyclonal Antibody (CAB5690) is a valuable tool for researchers studying the GRB7 protein, which is involved in cell signaling pathways related to cancer progression. This antibody, produced in rabbits, is highly reactive with human samples and has been validated for use in Western blot applications. By specifically binding to the GRB7 protein, this antibody enables accurate detection and analysis in a variety of cell types, making it an essential asset for studies in oncology and cancer research.
GRB7 is a signaling adaptor protein that plays a crucial role in promoting tumor growth, metastasis, and resistance to anti-cancer treatments. Understanding the function of GRB7 is essential for developing targeted therapies that can effectively combat these processes in various types of cancer. The GRB7 Polyclonal Antibody provides researchers with a reliable tool to further investigate the role of GRB7 in cancer development, progression, and treatment response.
Product Name:
GRB7 Rabbit Polyclonal Antibody
SKU:
CAB5690
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-140 of human GRB7 (NP_001229372.1).
The product of this gene belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules. This gene encodes a growth factor receptor-binding protein that interacts with epidermal growth factor receptor (EGFR) and ephrin receptors. The protein plays a role in the integrin signaling pathway and cell migration by binding with focal adhesion kinase (FAK). Several transcript variants encoding two different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
2886
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using GRB7 Rabbit pAb (CAB5690) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.
