GRB2 Rabbit Monoclonal Antibody (CAB19059)
- SKU:
- CAB19059
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Immunology
Frequently bought together:
Description
Product Name: | GRB2 Rabbit Monoclonal Antibody |
SKU: | CAB19059 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 118-217 of human GRB2 (P62993). |
Sequence: | YFLW VVKF NSLN ELVD YHRS TSVS RNQQ IFLR DIEQ VPQQ PTYV QALF DFDP QEDG ELGF RRGD FIHV MDNS DPNW WKGA CHGQ TGMF PRNY VTPV NRNV |
Tested Applications: | WB IHC-P IF/ICC IP ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 IP,0.5μg-4μg antibody for 200μg-400μg extracts of whole cells |
Synonyms: | ASH; Grb3-3; MST084; NCKAP2; MSTP084; EGFRBP-GRB2; GRB2 |
Positive Sample: | MCF7,293T,HL-60,HeLa,NIH/3T3,Mouse brain,Mouse kidney,Rat spleen,Rat brain |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Endosome, Golgi apparatus, Nucleus. |
Calculated MW: | 25kDa |
Observed MW: | 25kDa |
The protein encoded by this gene binds the epidermal growth factor receptor and contains one SH2 domain and two SH3 domains. Its two SH3 domains direct complex formation with proline-rich regions of other proteins, and its SH2 domain binds tyrosine phosphorylated sequences. This gene is similar to the Sem5 gene of C.elegans, which is involved in the signal transduction pathway. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 2885 |
Clone Number: | ARC0430 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |