GRB2 Rabbit Polyclonal Antibody (CAB5689)
- SKU:
- CAB5689
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Immunology
Frequently bought together:
Description
Product Name: | GRB2 Rabbit Polyclonal Antibody |
SKU: | CAB5689 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-217 of human GRB2 (NP_002077.1). |
Sequence: | MEAI AKYD FKAT ADDE LSFK RGDI LKVL NEEC DQNW YKAE LNGK DGFI PKNY IEMK PHPW FFGK IPRA KAEE MLSK QRHD GAFL IRES ESAP GDFS LSVK FGND VQHF KVLR DGAG KYFL WVVK FNSL NELV DYHR STSV SRNQ QIFL RDIE QVPQ QPTY VQAL FDFD PQED GELG FRRG DFIH VMDN SDPN WWKG ACHG QTGM FPRN YVTP VNRN V |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IF/ICC,1:10 - 1:100 |
Synonyms: | ASH; Grb3-3; MST084; NCKAP2; MSTP084; EGFRBP-GRB2; GRB2 |
Positive Sample: | SW620,Raji,BT-474,HepG2,Mouse heart |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Endosome, Golgi apparatus, Nucleus. |
Calculated MW: | 25kDa |
Observed MW: | 33kDa |
The protein encoded by this gene binds the epidermal growth factor receptor and contains one SH2 domain and two SH3 domains. Its two SH3 domains direct complex formation with proline-rich regions of other proteins, and its SH2 domain binds tyrosine phosphorylated sequences. This gene is similar to the Sem5 gene of C.elegans, which is involved in the signal transduction pathway. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 2885 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |