Granzyme B Rabbit Polyclonal Antibody (CAB2557)
- SKU:
- CAB2557
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Death
Frequently bought together:
Description
Product Name: | Granzyme B Rabbit Polyclonal Antibody |
SKU: | CAB2557 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 100-200 of human Granzyme B (NP_004122.2). |
Sequence: | YNPK NFSN DIML LQLE RKAK RTRA VQPL RLPS NKAQ VKPG QTCS VAGW GQTA PLGK HSHT LQEV KMTV QEDR KCES DLRH YYDS TIEL CVGD PEIK KTSF K |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 |
Synonyms: | C11; HLP; CCPI; CGL1; CSPB; SECT; CGL-1; CSP-B; CTLA1; CTSGL1; Granzyme B |
Positive Sample: | THP-1,Mouse large intestine |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasmic granule. |
Calculated MW: | 28kDa |
Observed MW: | 30kDa |
This gene encodes a member of the granzyme subfamily of proteins, part of the peptidase S1 family of serine proteases. The encoded preproprotein is secreted by natural killer (NK) cells and cytotoxic T lymphocytes (CTLs) and proteolytically processed to generate the active protease, which induces target cell apoptosis. This protein also processes cytokines and degrades extracellular matrix proteins, and these roles are implicated in chronic inflammation and wound healing. Expression of this gene may be elevated in human patients with cardiac fibrosis.
Purification Method: | Affinity purification |
Gene ID: | 3002 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.09% Sodium azide,50% glycerol,pH7.3. |