The GPX8 Polyclonal Antibody (AB30006) is specifically designed for research involving GPX8, a crucial enzyme in the antioxidant defense system of cells. This antibody, raised in rabbits, is highly reactive with human samples and has been validated for use in Western blot applications. It binds specifically to the GPX8 protein, allowing for its detection and analysis in a variety of cell types, making it an ideal tool for studies in oxidative stress, cancer research, and cellular defense mechanisms.GPX8, also known as glutathione peroxidase 8, plays a key role in protecting cells from oxidative damage by catalyzing the reduction of hydrogen peroxide and lipid hydroperoxides using glutathione as a cofactor.
Its importance in cellular defense mechanisms makes it a valuable target for research into diseases related to oxidative stress, such as cancer, neurodegenerative disorders, and cardiovascular diseases. Understanding the function of GPX8 is crucial for developing therapies that enhance cellular antioxidant capacity and combat oxidative stress-related conditions.
Product Name:
GPX8 Rabbit Polyclonal Antibody
SKU:
CAB20390
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 41-209 of human GPX8 (NP_001008398.2).
Enables peroxidase activity. Predicted to be involved in cellular response to oxidative stress. Predicted to be located in endoplasmic reticulum lumen.
Purification Method:
Affinity purification
Gene ID:
493869
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using GPX8 antibody (CAB20390) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
