The GPSM2 Polyclonal Antibody (CAB10553) is a powerful tool for researchers studying GPSM2, a multifunctional protein involved in various cellular processes. This antibody, carefully raised in rabbits, is highly specific to human samples and is validated for use in Western blot applications. By binding to the GPSM2 protein, this antibody allows for accurate detection and analysis in a range of cell types, making it an essential component for studies in cell biology and cancer research.GPSM2, also known as G-protein signaling modulator 2, plays a crucial role in cell signaling pathways and cellular organization.
Its diverse functions in cell proliferation, migration, and polarity make it a key player in various physiological processes. Research into GPSM2 can provide valuable insights into cancer progression, developmental disorders, and neurodegenerative diseases. Understanding the intricate mechanisms of GPSM2 can pave the way for the development of targeted therapies for a range of medical conditions.
Product Name:
GPSM2 Rabbit Polyclonal Antibody
SKU:
CAB10553
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 380-490 of human GPSM2 (NP_037428.3).
The protein encoded by this gene belongs to a family of proteins that modulate activation of G proteins, which transduce extracellular signals received by cell surface receptors into integrated cellular responses. The N-terminal half of this protein contains 10 copies of leu-gly-asn (LGN) repeat, and the C-terminal half contains 4 GoLoco motifs, which are involved in guanine nucleotide exchange. This protein may play a role in neuroblast division and in the development of normal hearing. Mutations in this gene are associated with autosomal recessive nonsyndromic deafness (DFNB82). Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
29899
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using GPSM2 Rabbit pAb (CAB10553) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
