The GPS2 Polyclonal Antibody (CAB3901) is a valuable tool for research involving GPS2, a key protein involved in transcriptional regulation and cellular signaling pathways. This rabbit polyclonal antibody is highly specific and sensitive towards GPS2 in human samples, making it ideal for applications such as Western blot analysis.GPS2, also known as G protein pathway suppressor 2, plays a crucial role in various cellular processes, including gene expression regulation and metabolic signaling. Dysregulation of GPS2 has been implicated in a variety of diseases, making it a promising target for research in fields such as cancer biology and metabolic disorders.
By using the GPS2 Polyclonal Antibody, researchers can accurately detect and analyze GPS2 protein levels in different cell types, providing insights into its functions and potential therapeutic relevance. This antibody is a valuable tool for studies aiming to uncover the role of GPS2 in disease development and progression, ultimately paving the way for the development of targeted interventions and therapies.
Antibody Name:
Anti-GPS2 Antibody
Antibody SKU:
CAB3901
Antibody Size:
20uL, 50uL, 100uL
Application:
WB IP
Reactivity:
Human, Mouse, Rat
Host Species:
Rabbit
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 200 to the C-terminus of mouse GPS2 (NP_062700.2).
This gene encodes a protein involved in G protein-mitogen-activated protein kinase (MAPK) signaling cascades. When overexpressed in mammalian cells, this gene could potently suppress a RAS- and MAPK-mediated signal and interfere with JNK activity, suggesting that the function of this gene may be signal repression. The encoded protein is an integral subunit of the NCOR1-HDAC3 (nuclear receptor corepressor 1-histone deacetylase 3) complex, and it was shown that the complex inhibits JNK activation through this subunit and thus could potentially provide an alternative mechanism for hormone-mediated antagonism of AP1 (activator protein 1) function.
